Role of Green Tea Extracts on Chromatin Remodeling of Telomerase Gene in Cancer Cells (2004)

Title:

Role of Green Tea Extracts on Chromatin Remodeling of Telomerase Gene in Cancer Cells

Key words:

Green tea, EGCG

Research Institution:

University of Alabama at Birmingham

Location:

Alabama

Researcher:

Liang Liu

Project Description:

This postdoctoral study investigated the effects of the green tea catechin, (-)-epigallocatechin-3-gallate (EGCG), on telomerase gene expression in MCF-7 breast cancer cells and human teratocarcinoma cells to determine if the down regulation of this gene is the mechanism by which EGCG induces apoptosis of cancer cells.