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Enhancement of the Response of Breast Tumor Cells to Fractioned Radiation by Ananlogs of Vitamin D3 (2002)

Title:

Enhancement of the Response of Breast Tumor Cells to Fractioned Radiation by Ananlogs of Vitamin D3

Key words:

vitamin D3, p53 gene, ceramide

Research Institution:

Virginia Commonwealth University

Location:

Virginia

Researcher:

David A Gewirtz

Project Description:

Dr. Gewirtz studied the mechanism by which vitamin D analogs and radiation cause some human breast cancer cells in culture to die out, either through the action of the cell signaling molecule ceramide, or through mutations in the p53 gene.

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