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The Function of PML-RARx During All-trans Retinoic Acid Induced Differentiation in Acute Promyelocytic Leukemia (2001)

Title:

The Function of PML-RARx During All-trans Retinoic Acid Induced Differentiation in Acute Promyelocytic Leukemia

Key words:

cathepsin B, trans-retinoic acid, acute promylocytic leukemia

Research Institution:

Mount Sinai School of Medicine

Location:

New York

Researcher:

Yongkui Jing

Project Description:

Dr. Jing studied further the relationship between cathepsin B induction by trans-retinoic acid and the cleavage of certain retinoic acid receptors, leading to differentiation of acute promyelocytic leukemia cells.

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