Abnormal Receptor for a Vitamin A Derivative in Promyelocytic Leukemia (2001)

Title:

Abnormal Receptor for a Vitamin A Derivative in Promyelocytic Leukemia

Key words:

retinoic acid receptors, acute promyelocytic leukemia

Research Institution:

University of Pittsburgh

Location:

Pennsylvania

Researcher:

Robert L Redner

Project Description:

Dr. Redner investigated, through study of fusion protein formed from the retinoic acid receptor gene and the amino terminus of the nucleophosmin gene, how retinoic acid reverses the differentiation defect in acute promyelocytic leukemia.

Cancer Site(s)

Blood/Bone Marrow/Lymph

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