David Christiani, MD
Vitamin D and esophageal cancer survivors
Obesity is a clear risk factor for esophageal cancer. Other research suggests that Vitamin D levels and variations in vitamin D metabolizing genes increase the risk of developing esophageal cancer.
Yet the association of all these factors with esophageal survival remains unknown, says Christiani. "Vitamin D has a number of properties that may be beneficial in survival, like inhibiting metastases. Moreover, vitamin D levels are determined, in part, by genetic variations in the vitamin D receptor genes," he says.
Christiani will look at DNA, serum vitamin D and other data from approximately 700 esophageal cancer patients. The findings will hopefully provide data on how multiple factors affect survival, says Christiani.